TABLE 8.

Effect of treatment on depressive symptoms, quality of life, and anxiety.

	Mean (DP)					Delta % (D-A)	p value
	Day 1 (A)	Day 15 (B)	Day 30 (C)	Day 60 (D)	Follow up (E)
tDCSa	n = 13	n = 11	n = 12	n = 9	n = 10
tDCSs	n = 13	n = 9	n = 11	n = 10	n = 8
BDI-II
tDCSa	28.5 ± 5.5	23.0 ± 10.6	18.5 ± 9.9	16.0 ± 8.1	17.0 ± 8.8	−43.93%
tDCSs	27.3 ± 7.2	19.8 ± 7.4	13.9 ± 9.3	15.1 ± 11.4	19.3 ± 8.2	−44.67%
Intervention effect							0.42
Time							< 0.001
Interaction time*Intervention							0.93
QOLIE-31
tDCSa	47.7 ± 13.0	–	58.1 ± 17.1	59.8 ± 17.7	62.8 ± 20.9	25.51%
tDCSs	50.5 ± 13.5	–	58.4 ± 16.5	61.1 ± 11.8	59.6 ± 13.0	20.91%
Intervention effect							0.9
Time							0.003
Interaction time*Intervention							0.92
HAM-A
tDCSa	23.3 ± 8.3	–	21.2 ± 8.3	20.8 ± 10.2	–	−10.07%
tDCSs	22.9 ± 4.2	–	23.8 ± 7.5	17.7 ± 6.1	–	−22.42%
Intervention effect							0.86
Time							0.05
Interaction time*Intervention							0.09

Data were analyzed through Generalized Estimating Equations with a dependent variable (BDI-II, QOLIE-31, or HAM-A score), within-subject variable (time) and variable between subjects (active × Sham tDCS). Bonferroni was the post hoc analysis.