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Synthesis of analogs 49, 50, 52, 54, 56 and 58. Reaction Conditions: (a) 1-isocyanato-4-isopropylbenzene (1.1 eq), Et2O, rt, 3 h; (b) TFA-CH2Cl2 (1:1), rt, 1 h; (c) 6-chloronicotinonitrile (1.1 eq), Et3N (2 eq), acetonitrile, MW, 160 °C, 30 min.
