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. Author manuscript; available in PMC: 2021 Dec 22.
Published in final edited form as: Bioorg Med Chem. 2021 Nov 12;52:116504. doi: 10.1016/j.bmc.2021.116504

Figure 3.

Figure 3.

Crystal structures of PANK3 in complex with 4 inhibitors. A. Compound 31 (cyan carbons) (PDB 6X4J); B. Compound 55 (purple carbons) (PDB 6X4L); C. Compound 56 (yellow carbons) (PDB 6X4K); D. Compound 57 (PZ-2891, magenta carbons) (PDB 6B3V). The views are identical in each figure. Monomer A (that contains the bound AMPPNP) is colored orange and monomer B (residues indicated with a prime) is colored green.