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. 2021 Nov 26;15:785057. doi: 10.3389/fncel.2021.785057

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Copyright © 2021 Seminotti, Grings, Tucci, Leipnitz and Saso.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Schematic diagram showing the role of oxidative stress and Nrf2 modulation in the neuropathophysiology of IMD. IMD, Inherited Metabolic Disorders; Nrf2, nuclear factor erythroid-2-related factor 2.