Reaction of β-bromo-β-nitrostyrene 1a with 1,3-diphenylthiourea 2a under different conditions.

Entrya	Base	Solvent	Temperature (°C)	Time (h)	Yield (%)
1	K2CO3	THF	rt	24	62
2b	K2CO3	THF	70	10	60
3	Et3N	THF	rt	24	72
4b	Et3N	THF	70	10	65
5	DBU	THF	rt	24	63
6b	DBU	THF	70	10	58
7	KHCO3	THF	rt	24	55
8b	KHCO3	THF	70	10	60
9	DIPEA	THF	rt	24	68
10	None	THF	rt	24	29
11c	Et3N	THF	rt	24	64
12d	Et3N	THF	rt	24	58
13e	Et3N	THF	rt	24	17
14	Et3N	CH2Cl2	rt	24	45
15	Et3N	Toluene	rt	24	42
16b	Et3N	Toluene	110	5	40

^aReactions were performed with β-bromo-β-nitrostyrene 1a (0.10 mmol) and 1,3-diphenylthiourea 2a (0.11 mmol) with base (0.02 mmol) in the indicated solvent (2.0 mL) under atmospheric air.

^bβ-Bromo-β-nitrostyrene was completely consumed.

^cReaction was carried out with 0.04 mmol of base.

^dReaction was carried out with 0.01 mmol of base.

^eReaction was carried out with 0.1 mmol of base.