Comparison 3. Pain.

Outcome or subgroup title	No. of studies	No. of participants	Statistical method	Effect size
1 Pain Perception	25	1705	Mean Difference (IV, Random, 95% CI)	‐9.09 [‐14.03, ‐4.14]
1.1 Pain Score 1st Postoperative Day	25	729	Mean Difference (IV, Random, 95% CI)	‐9.30 [‐13.19, ‐5.42]
1.2 Pain Score 2nd Postoperative Day	25	757	Mean Difference (IV, Random, 95% CI)	‐7.85 [‐18.87, 3.18]
1.3 Pain Score 3rd Postoperative Day	25	219	Mean Difference (IV, Random, 95% CI)	‐12.88 [‐19.74, ‐6.02]