Table 4.
Antibodies detecting MHC molecules on tumour tissue | Cumulative % of positive tumour tissuea | Cohort | WP | BP (HLA-A02*)b | P (χ2)c |
---|---|---|---|---|---|
N | 162% | 47% | 115 (45)% | ||
HC-10 | <50% (low) | 27 | 48 | 19 (6.5) | <0.001 (14.6) |
≥50% (high) | 73 | 52 | 81 (93.5) | <0.001 (18.8) | |
HCA | <50% (low) | 41 | 53 | 35.5 (11) | 0.04 (4.5) |
≥50% (high) | 59 | 47 | 64 (8.9) | 0.02 (5.1) | |
L368 | <50% (low) | 64 | 81 | 57.5 (30.4) | 0.02 (5.7) |
≥50% (high) | 36 | 19 | 42.5 (69.6) | <0.001 (11.3) |
a<50% staining scores (low) and >50% staining scores (high)
bIn paranthesis are presented the fraction of HLA-A02* patients
cComparison between % of WP and BP for low and high respectively. P values and χ2