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. 2012 Jan 19;61(8):1243–1253. doi: 10.1007/s00262-012-1201-0

Table 4.

Distribution of mAbs detecting <50% or equal/more than 50% MHC molecules on the tumour tissue

Antibodies detecting MHC molecules on tumour tissue Cumulative % of positive tumour tissuea Cohort WP BP (HLA-A02*)b P2)c
N 162% 47% 115 (45)%
HC-10 <50% (low) 27 48 19 (6.5) <0.001 (14.6)
≥50% (high) 73 52 81 (93.5) <0.001 (18.8)
HCA <50% (low) 41 53 35.5 (11) 0.04 (4.5)
≥50% (high) 59 47 64 (8.9) 0.02 (5.1)
L368 <50% (low) 64 81 57.5 (30.4) 0.02 (5.7)
≥50% (high) 36 19 42.5 (69.6) <0.001 (11.3)

a<50% staining scores (low) and >50% staining scores (high)

bIn paranthesis are presented the fraction of HLA-A02* patients

cComparison between % of WP and BP for low and high respectively. P values and χ2