Table 5.
Proportional hazard regression and time to death. Comparison between MHC class I products and HLA genotype
| Strata | Factors | Univariate analysis | Multivariate analysis | ||||
|---|---|---|---|---|---|---|---|
| HR | 95% CI | P | HR | 95% CI | P | ||
| All patients not stratified | WP versus BP | 3.3 | 2.2–4.9 | <0.001 | 3.2 | 2.1–4.9 | <0.001 |
| HC10 low versus high | 1.7 | 1.1–2.5 | 0.01 | 1.14 | 0.65–1.99 | 0.64 | |
| HCA low versus high | 1.50 | 1.01–2.2 | 0.02 | 1.37 | 0.8–2.3 | 0.24 | |
| L368 low versus high | 1.27 | 0.86–1.9 | 0.22 | 0.79 | 0.49–1.3 | 0.34 | |
| HLA-A02* | WP versus BP | 5.4 | 3–10 | <0.001 | 5.8 | 3.1–10.9 | <0.001 |
| HC10 low versus high | 1.8 | 1–3.2 | 0.05 | 1.3 | 0.5–3.2 | 0.54 | |
| HCA low versus high | 1.5 | 0.9–2.6 | 0.1 | 0.9 | 0.4–2.3 | 0.99 | |
| L368 low versus high | 1.34 | 0.83–2.1 | 0.23 | 0.7 | 0.4–1.3 | 0.31 | |