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. Author manuscript; available in PMC: 2021 Dec 22.
Published in final edited form as: Expert Opin Drug Discov. 2020 Feb 26;15(5):551–560. doi: 10.1080/17460441.2020.1732920

Fig 3.

Fig 3.

A model proposing that direct binding of EPI to Tau-5 in the AR-NTD creates a conformation that prevents interactions with CBP and the basal transcriptional machinery (BTM).