Fig. 2. Web interface of the MeFSAT database. (a) Snapshot of the result of a standard query for secondary metabolites of a medicinal fungus. The example shows the secondary metabolites for the fungus Boletus edulis. (b) Snapshot of the detailed information page for a secondary metabolite which gives its 2D and 3D chemical structure, physicochemical properties, drug-likeness properties, predicted ADMET properties, molecular descriptors and predicted human target proteins. From this page, users can download the 2D and 3D structure of the secondary metabolite in SDF, MOL, MOL2, PDB or PDBQT file formats. The example shows information for the secondary metabolite trametenolic acid B. (c) Snapshot of the result of a standard query for therapeutic uses of a medicinal fungus. The example shows the therapeutic uses for the fungus Boletus edulis. (d) Snapshot of the advanced search options which enable users to filter secondary metabolites based on their physicochemical properties or drug-likeness properties or chemical similarity with a query chemical structure in SMILES format.