Table 3.
Associations (HR (95% CI)) a between LAN and incidence of pancreatic cancer by BMI in the NIH-AARP Diet and Health Study.
| BMI, kg/m2 | No. of cases/Total N | LAN in 1996 | p-trend | Per quintile increase | ||||
|---|---|---|---|---|---|---|---|---|
| Q1 | Q2 | Q3 | Q4 | Q5 | ||||
| <25 | 825/160,589 | ref | 0.99 (0.76, 1.29) | 1.13 (0.85, 1.50) | 1.12 (0.83, 1.51) | 1.30 (0.94, 1.80) | 0.08 | 1.07 (0.99, 1.15) |
| 25–<30 | 1,072/193,327 | ref | 0.95 (0.76, 1.19) | 1.07 (0.84, 1.37) | 1.19 (0.92, 1.54) | 1.31 (0.98, 1.74) | 0.02 | 1.09 (1.02, 1.16) |
| 30+ | 605/110,455 | ref | 0.91 (0.68, 1.23) | 1.17 (0.85, 1.61) | 1.04 (0.74, 1.47) | 1.04 (0.71, 1.52) | 0.65 | 1.02 (0.94, 1.11) |
adjusted for state of residence (California, Florida, Louisiana, New Jersey, North Carolina, Pennsylvania, Georgia, Michigan), sex (men, women), race (white, black, other), education (less than high school, high school graduate, some college, college and post graduate), smoking (former smoker and quit 10+ years, former smoker and quit 1–9 years, current smoker or quit<1 year, never smoked), alcohol (non-drinker, <1 drink/day, 1–<3 drinks/day, ≥3 drink/day), red meat intake (continuous), rural-urban continuum code (1, 2, 3, 4, 5+), and 2000 census tract poverty rate (continuous), median home value (continuous), and population density (quintile).
P-interaction=0.03