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. Author manuscript; available in PMC: 2022 Jul 1.
Published in final edited form as: Clin Pharmacol Ther. 2021 Mar 11;110(1):82–97. doi: 10.1002/cpt.2166

Figure 4. In-silico modelling highlighting regions with potential misalignments from simulated reference CYP2B6 short-read sequences.

Figure 4

Panel A and B display simulated single-end reads ranging from 50 to 1,000 bases in length and paired-end reads from 100 to 150 bases and insert sizes from 300 to 800 bases, respectively. Reads that uniquely mapped to CYP2B6 with the BWA-mem aligner are shown in light blue and exons to which reads could tentatively also align elsewhere are hatched in darker blue.