Formation of C(sp2)–X (X = N, O, P, S, and Se) bonds on DNA.
Entry | DNA-compatible reactions | Conditions |
---|---|---|
1 | CsOH, DMA, 100 °C | |
2 | Water, DMA, NaOH | |
3 | Buchwald–Hartwig cross-coupling | |
4 | DMA, CsOH, 80 °C-95 °C | |
5 | KOH, sodium ascorbate, H2O, DMA | |
6 | Sodium ascorbate, K3PO4, DMSO/water, 40 °C, 3 h | |
7 | RASS, DMA, MS | |
8 | K2CO3, DMA | |
9 | Phosphonic chloride, 4,4′-di-tertbutyl bipyridine | |
10 | K2CO3 or KOH, DMA + H2O, RT or 60 °C | |
11 | K2CO3, DMA + H2O, RT or 80 °C | |
12 | DCE, 100 °C, 1 h |