Multicomponent reaction on DNA.
| Entry | DNA-compatible reactions | Conditions |
|---|---|---|
| 1 |
|
DMF/TEOF, 50 °C, 24 h |
| 2 |
|
THF, RT, 20 h |
| 3 |
|
CH2Cl2/triethyl orthoformate, RT, 4 h |
| 4 |
|
ACN/triethyl orthoformate, RT, 6 h |
| 5 |
|
MeCN/TEOF, RT, 4 h; MeCN, RT, 1 h; NH3, 50 °C, 6 h |
| 6 |
|
Ugi 4-component reaction |
| 7 |
|
Ugi–Azide 4-component reaction |
| 8 |
|
Ugi 4-component/aza-Wittig reaction |
| 9 |
|
Groebke–Blackburn–Bienayme 3-component reaction |
| 10 |
|
DMSO, RT, 18 h |
| 11 |
|
Morpholine,aq. DMA, 45 °C |