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. 2021 Dec 22;9(3):e01164-21. doi: 10.1128/Spectrum.01164-21

FIG 1.

FIG 1

Global distribution of tet(X)s from human microbiome. (a) World map showed the positive rates of tet(X) gene in 19 countries and the colored countries represented the positive rates of tet(X) according to the hot map (>0–9.40%) at the bottom. The gray countries indicated they were negative for tet(X) gene. The size of the pie charts represented the numbers of tet(X)-positive MAGs and the colors in the pie charts indicated the composition of tet(X) variants. (b) PhyloPhlAn analysis of the tet(X) carrying MAGs. The taxonomic assignments of the tet(X)-carrying MAGs were depicted with colored circles in the phylogenetic tree. The tet(X) variants carried by the MAGs, as well as oxygen demand, Gram stain, age category and the countries of the tet(X)-carrying MAGs were showed in the five colored rings surrounding the phylogenetic tree. (c) Distribution of the 12 MAGs carried non-tet(X2) genes with tigecycline inactivate function.