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. 2021 Nov 1;32(21):ar28. doi: 10.1091/mbc.E21-01-0010

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FIGURE 4: — ARHGAP4 down-regulates FAs in HEK293 cells via its Rho-GAP domain and SH3 domain. (A) Immunoblot shows that ARHGAP4 lowers the paxillin and FAK expression, to which the F-BAR domain partly contributes and the Rho-GAP/SH3 domains contribute more significantly. (B) Quantification of A with the mean and SD. (C) Immunofluorescence of paxillin in cells overexpressed with EGFP, EGFP-labeled paxillin, and its mutants, and its quantification with the mean and SD. Scale, 20 µm.