Enzyme inhibiting efficacies of 1–13 toward rat intestinal disaccharidases^a.

Compound	Sucrase	Isomaltase	Maltase
1	1.6b	5.2b	5.2b
2	3.6	0.45	25
3 (H)	0.44c	0.14c	0.32c
4 (o-CH3)	0.41c	0.48c	0.66c
5 (o-Cl)	0.090c	0.26c	0.31c
6 (o-CF3)	0.15c	0.19c	0.33c
7 (o-NO2)	0.042c	0.21c	0.13c
8 (3′-epi-1)	19	6.4	>100
9 (3′-epi-2)	0.69	0.58	4.3
10 (2′-epi-1)	>100	>100	>100
11 (2′-epi-2)	85	>100	>100
12 (2′,3′-epi-1)	>100	>100	>100
13 (2′,3′-epi-2)	84	34	>100
Voglibose	0.20d	2.1d	1.2d
Acarbose	1.5e	646e	1.7e

^aApparent IC₅₀ in (μM).

^bRef. 24.

^cRef. 32.

^dRef. 35.

^eRef. 36.