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. 2021 Dec 22;12(1):561–577. doi: 10.1039/d1ra08055e

In vitro antimicrobial activities of the synthesized compounds using well diffusion agar assay and expressed as mean diameter of inhibition zones (mm).

Mean diameter of inhibition zone (mean ± SEM) (mm)
Cpd. no. Gram +ve bacteria Gram −ve bacteria Fungi
S. aureus 25923 E. faecalis S. pneumoniae 010010 E. coli RCMB 010052 S. typhi ATCC 14028 P. aeruginosa A. fumigatus RCMB 02568 C. albicans ATCC 10231
1 31 ± 0.17 28 ± 0.92 30 ± 0.87 26 ± 0.22 21 ± 0.54 27 ± 0.51 25 ± 0.88 22 ± 0.30
3a 28 ± 0.15 13 ± 0.76 21 ± 0.69 25 ± 0.15 17 ± 0.95 22 ± 0.44 18 ± 0.25 12 ± 0.51
3b 19 ± 0.68 20 ± 0.24 14 ± 0.84 15 ± 0.71 23 ± 0.79 17 ± 0.41 21 ± 0.22 11 ± 0.70
3c 30 ± 0.47 27 ± 0.36 25 ± 0.17 28 ± 0.92 21 ± 0.16 23 ± 0.13 24 ± 0.15 18 ± 0.67
3d 13 ± 0.95 22 ± 0.11 28 ± 0.45 22 ± 0.14 18 ± 0.13 20 ± 0.19 19 ± 0.45 16 ± 0.28
5a 21.2 ± 0.25 13 ± 0.43 NA NA 23 ± 0.05 NA 9 ± 0.53 NA
5b 16 ± 0.88 27 ± 0.41 28 ± 0.12 10 ± 0.42 NA 18 ± 0.95 NA 12 ± 0.07
5c 20 ± 0.08 24 ± 0.89 15 ± 0.86 25 ± 0.10 17 ± 0.78 22 ± 0.48 26 ± 0.17 19 ± 0.23
5d 25 ± 0.13 NA NA 15 ± 0.04 NA 13 ± 0.11 NA NA
aS 26 ± 0.45 25 ± 0.38 22 ± 0.81 27 ± 0.56 23 ± 0.92 20 ± 0.53
aA 22 ± 0.72 20 ± 0.78
a

Streptomycin and Amphotericin B were used as standard drugs against the tested bacteria and fungi, respectively.