FIG. 9.

Physical and genetic interactions among CTF4, CTF18, CTF7, and DNA synthesis proteins. The bold circles denote replication-associated proteins affecting sister chromatid cohesion. Physical associations are indicated by symbol overlap, synthetic lethality is indicated by solid lines with double arrows, and synthetic dosage lethality is indicated by dashed lines with single arrows. The interactions are described in this work [1] and references 87 [2], 112 [3], 24 [4], 69 [5], 11 [6], 56 [7], 4 [8], 28 [9], 67 [10], 114 [11], and 27 [12]. The physical interactions among RF-C subunits are described in references 17, 23, 75, and 104.