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. 2021 Dec 8;9:772436. doi: 10.3389/fcell.2021.772436

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Copyright © 2021 Xu, Zhu, Tian, Liu, Wu, Anwaier, Su, Wei, Qu, Zhang and Ye.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Relation of m⁵C modification with clinicopathological features and tumor somatic mutation. (A–F) Associations of m⁵C score with stage, grade, age, gender, PBRM1 mutation status, and TMB in TCGA cohort. (G–H) Landscapes of somatic variants of high and low m⁵C score groups in TCGA cohort. (I–J) Copy number variants of high and low m⁵C score groups in TCGA cohort.