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. 2021 Dec 8;9:772436. doi: 10.3389/fcell.2021.772436

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Copyright © 2021 Xu, Zhu, Tian, Liu, Wu, Anwaier, Su, Wei, Qu, Zhang and Ye.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Characteristics of TME and immune cell distribution in m⁵C-related phenotypes. (A) GSVA results of high and low m⁵C score groups based on expression profiles from CPTAC and TCGA cohorts. (B) Estimation of immune cell infiltration in high and low m⁵C score groups. (C) Expression levels of chemokines, cytokines, and immune checkpoints between high and low m⁵C score groups.