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. 2021 Dec 8;9:772436. doi: 10.3389/fcell.2021.772436

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Copyright © 2021 Xu, Zhu, Tian, Liu, Wu, Anwaier, Su, Wei, Qu, Zhang and Ye.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Influence of m⁵C modification patterns on chemotherapy and immunotherapy response. (A–B) IC50 value for cisplatin and gemcitabine in low and high m⁵C score groups. (C) TIDE prediction score of low and high m⁵C score groups. (D) ROC curve for evaluating the ability of m⁵C score to predict immunotherapy response.