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. Author manuscript; available in PMC: 2022 Jan 1.
Published in final edited form as: Nat Neurosci. 2021 May 10;24(7):1035–1045. doi: 10.1038/s41593-021-00849-x

Extended Data Figure 9. Increased excitability of mPFC pyramidal neurons after stimulation.

Extended Data Figure 9.

a, Image of viral expression of ChR2.mCherry and probe placement. Scale bar, 500 μm. b, Images of c-Fos immunoreactivity in ipsilateral mPFC, interconnected contralateral mPFC, and ipsilateral M1 as a control region. Scale bar, 20 μm. c, Summary data show average c-Fos intensity in individual mice (left), the distribution of c-Fos neuronal particle intensities (middle), and cumulative frequency of c-Fos particle intensities. RM one-way ANOVA, P = 0.0025, Sidak’s multiple comparisons test, ipsilateral (ip) mPFC vs ipsilateral M1, P = 0.0201, contralateral (con) mPFC vs ipsilateral M1, P = 0.0370. N = 4 mice/group. Data represent mean +/− SEM; dashed lines in the violin plot show quantiles and median. * P < 0.05.