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. 2021 Jan 20;11(7):3897–3916. doi: 10.1039/d0ra08905b

Effect of test compounds on cotton pellet induced granuloma in ratsa.

Treatment and dose (100 mg kg−1, p.o.) Weight (mg) mean ± SEM
Wet Dry
Control 250.30 ± 1.48 123.30 ± 1.48
8b 182.50 ± 1.77*# 84.10 ± 1.67*#
8c 148.62 ± 1.85*## 91.30 ± 1.72*#
8e 152.40 ± 1.57*## 76.45 ± 1.95*##
8f 139.82 ± 2.42*## 70.66 ± 2.33*##
8g 190.90 ± 1.84*# 78.42 ± 2.04*#
Celecoxib 150.14 ± 3.46** 78.80 ± 3.24**
a

**p < 0.01, *p < 0.05 when compared with normal control group. ##p < 0.01, #p < 0.05 when compared with standard group.