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. 2021 Dec 18;14:6993–7006. doi: 10.2147/JIR.S340351

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© 2021 Chen et al.

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The workflow of study was displayed.

Abbreviations: ALB, albumin; anti-CCP, anti-cyclic citrullinated peptide antibody positive rate; CRP, C reactive protein; CDAI, clinical disease activity index; DAS28-CRP, disease activity score of 28 joints for C reactive protein; DAS28-ESR, disease activity score of 28 joints for erythrocyte sedimentation rate; DEPs, differentially expressed proteins; ESR, erythrocyte sedimentation rate; HAQ, health assessment questionnaire; iTRAQ, isobaric tags for relative and absolute quantification; NRs, non-responders; PGA, physician’s global assessment; PtGA, patient’s global assessment; PRM, parallel reaction monitoring; RF, rheumatoid factor; Rs, responders; SDAI, simplified disease activity index; SJC, swollen joint count; TJC, tender joint count; VAS, visual analogue scale.