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. 2021 Dec 22;16(12):e0261656. doi: 10.1371/journal.pone.0261656

Fig 5. The phenotype of T-bet+ IgG+ spike-specific B cells.

Fig 5

A) UMAPS showing the expression of individual markers in T-bet+ IgG+ spike-specific B cells. B) Gating of four populations of T-bet+ IgG+ B cells based on unique expression profiles of the markers shown in panel A. C) Distribution of the four T-bet+ IgG+ B cell population among individuals who recovered from non-severe (n = 7) and severe (n = 5) COVID-19. D) Summary of the phenotype of the four T-bet+ IgG+ B cell populations identified here and their classification into one of the major B cell subsets: activated switched memory (act. swM), DN2, or resting switched memory (rest. swM) B cells.