Acute oral toxicity of saponin on the food intake, body weight and food utilization rate in ratsa.
| Sex | Saponin dose (g per kg per body weight) | Food intake (g) | Body weight (g) | Food utilization rate (%) |
|---|---|---|---|---|
| Male | 0 | 444.00 ± 6.07 | 138.00 ± 10.66 | 31.06 ± 1.84 |
| 1 | 420.00 ± 7.32** | 106.00 ± 14.78* | 25.35 ± 2.88* | |
| 2.15 | 410.00 ± 6.98** | 95.00 ± 9.66** | 23.14 ± 2.05** | |
| 4.64 | 428.00 ± 7.57** | 108.00 ± 17.78* | 25.28 ± 4.39* | |
| 10 | 375.00 ± 9.29** | 97.00 ± 13.57** | 25.68 ± 2.80* | |
| Female | 0 | 262.00 ± 4.56 | 67.00 ± 9.27 | 25.54 ± 3.09 |
| 1 | 247.00 ± 5.01* | 51.00 ± 3.81* | 20.63 ± 1.12* | |
| 2.15 | 233.00 ± 7.68** | 44.00 ± 6.53** | 18.84 ± 2.18** | |
| 4.64 | 242.00 ± 8.52* | 46.00 ± 0.57** | 19.02 ± 0.43** | |
| 10 | 226.00 ± 13.10** | 44.00 ± 10.58** | 19.33 ± 3.57* |
All data are means ± standard deviation (n = 5 in each group, **Significant difference at P < 0.01 level when compared with the control group, *Significant difference at P < 0.05 level when compared with the control group).