Table 3.
Adjusted ORs and 95% CIs for OSA (AHI>5 Events/h) Risk According to HTGW Phenotypes Categorised by Age, Sex and BMI
| Subgroup | Cases/Controls | NTNW | HTNW, OR (95% CI) | NTGW, OR (95% CI) | HTGW, OR (95% CI) | p for Trend |
|---|---|---|---|---|---|---|
| Age | ||||||
| <60 | 2231/590 | 1.00 | 1.35(0.86–2.12) | 2.62(1.96–3.51)* | 3.70(2.57–5.32)* | <0.001 |
| ≥60 | 326/43 | 1.00 | /# | 1.47(0.60–3.60) | 3.80(1.22–11.89)* | 0.130 |
| Sex | ||||||
| Male | 2141/371 | 1.00 | 1.15(0.71–1.87) | 1.95(1.38–2.74)* | 2.80(1.85–4.24)* | <0.001 |
| Female | 416/262 | 1.00 | 3.04(0.92–10.01) | 3.93(2.37–6.52)* | 6.79(3.46–13.33)* | <0.001 |
| BMI | ||||||
| <24 | 472/335 | 1.00 | 0.95(0.52–1.72) | 2.40(1.58–3.62)* | 3.32(1.61–6.81)* | <0.001 |
| ≥24 | 2085/298 | 1.00 | 2.32(1.08–4.96)* | 2.38(1.53–3.71)* | 3.71(2.30–5.99)* | <0.001 |
Notes: Model 1 Adjusted for age and sex. Model 2 Adjusted for model 1 covariates plus BMI, smoking status, alcohol consumption. Model 3 Adjusted for model 2 covariates plus hypertension, diabetes, low-density lipoprotein, high-density lipoprotein, and total cholesterol. *Indicated statistical significance; #The sample size is too small, thus the OR (95% CI) cannot be calculated.
Abbreviations: ORs, odds ratios; 95% CIs, 95% confidence intervals; OSA, obstructive sleep apnea; HTGW, hypertriglyceridemic waist; BMI, body mass index; NTNW, normal TG and normal WC; HTNW, elevated TG and normal WC; NTGW, normal TG and enlarged WC.