Table 4.
Univariate and Multivariate Logistic Regression Analysis of Intestinal Flora Imbalance in Patients with Stable COPD
Predictors | Univariate Analysis | Multivariate Analysis | ||||||
---|---|---|---|---|---|---|---|---|
β value | OR | P value | 95%CI | β value | OR | P value | 95%CI | |
BMI | -2.070 | 0.126 | <0.001* | 0.058–0.272 | -2.406 | 0.090 | <0.001* | 0.026–0.317 |
FEV1%pred | -1.001 | 0.367 | 0.012* | 0.168–0.807 | 2.010 | 7.460 | 0.161 | 0.450–123.767 |
ALB | -1.738 | 0.176 | <0.001* | 0.084–0.369 | -1.280 | 0.278 | 0.040* | 0.082–0.945 |
PaO2 | -0.792 | 0.453 | 0.055 | 0.202–1.016 | NS | – | – | – |
CCI score | 3.353 | 28.597 | <0.001* | 11.693–69.938 | 3.244 | 25.633 | <0.001* | 6.652–98.775 |
mMRC score | 1.344 | 3.834 | 0.002* | 1.626–9.044 | 1.454 | 4.281 | 0.094 | 0.782–23.427 |
CAT score | 1.212 | 3.360 | 0.002* | 1.571–7.186 | 0.093 | 1.097 | 0.894 | 0.280–4.302 |
GSRs score | 2.633 | 13.914 | <0.001* | 5.595–34.605 | 2.840 | 17.113 | <0.001* | 4.012–72.997 |
GOLD classification | 1.235 | 3.437 | 0.004* | 1.491–7.923 | 3.237 | 25.469 | 0.034* | 1.276–508.213 |
Constant | – | -4.332 | 0.013 | 0.009 |
Notes: *Compared with control group, P<0.05. COPD prediction model equation and performance using the aforementioned five independent variables. The logit model to determine PRE_1 was expressed as follows: Logit(p) = -4.332 + (-2.406 BMI) + (-1.280 ALB) + (3.244 CCI score) + (2.840 GSRs score) + (3.237 GOLD classification); ; e: natural logarithm (~2.718); x= -4.332 + (-2.406 BMI) + (-1.280 ALB) + (3.244 CCI score) + (2.840 GSRs score) + (3.237 GOLD classification).
Abbreviation: NS, No statistical significance.