Pharmacokinetic parameters after administration in rats (n = 6)^a.

Parameter	LO	LS
t 1/2 (min)	164.7 ± 26.39	214.9 ± 151.4
C max (μg mL−1)	1.92 ± 0.12	2.29 ± 0.15***
T max (min)	40.0 ± 0.35	60.0 ± 0.42
AUC0–t (μg mL−1 min−1)	116.2 ± 6.45	373.2 ± 15.96***
AUC0–∞ (μg mL−1 min−1)	147.9 ± 10.51	452.9 ± 85.81***
MRT0–t (min)	63.01 ± 7.19	155.5 ± 3.33***
MRT0–∞ (min)	154.6 ± 18.91	282.9 ± 126.9***
Fr (%)	—	323.0 ± 31.66

^a***P < 0.001, *P < 0.05.