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. 2021 Dec 23;40(3):437–443. doi: 10.1016/j.vaccine.2021.12.012

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Since January 2020 Elsevier has created a COVID-19 resource centre with free information in English and Mandarin on the novel coronavirus COVID-19. The COVID-19 resource centre is hosted on Elsevier Connect, the company's public news and information website. Elsevier hereby grants permission to make all its COVID-19-related research that is available on the COVID-19 resource centre - including this research content - immediately available in PubMed Central and other publicly funded repositories, such as the WHO COVID database with rights for unrestricted research re-use and analyses in any form or by any means with acknowledgement of the original source. These permissions are granted for free by Elsevier for as long as the COVID-19 resource centre remains active.

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Fig. 2 — SARS-CoV-2 anti-RBD antibody log-scale responses for (A) weekly change for 4 weeks, (B) monthly. Change for 12 weeks. SARS-CoV-2 anti-RBD antibodies (C) change according to age groups, (D) regression model, and (E) heatmap for individuals. SARS-CoV-2, severe acute respiratory syndrome coronavirus 2; RBD, receptor-binding domain of viral spike protein.