Anti-inflammatory activities of compounds (60–63) (reproduced with permission from O. I. Abd El-Salam, et al., Egypt. J. Chem., 2012, 55, 529–547, © 2012, Egyptian Chemical Society)90.
| Compound no. | Anti-inflammatory activity | ||
|---|---|---|---|
| Dose, mg kg−1 p.o. | % inhibition of oedema | % inhibition of PGE2 | |
| 60 | 2.5 | 80.55 | 90.98 |
| 5 | 89.35 | 96.89 | |
| 61 | 2.5 | 85.32 | 83.98 |
| 5 | 91.06 | 90.00 | |
| 62 | 2.5 | 82.98 | 77.98 |
| 5 | 87.98 | 86.00 | |
| 63 | 2.5 | 94.20 | 85.31 |
| 5 | 95.88 | 92.09 | |
| Diclofenac potassium | 2.5 | 81.09 | 75.89 |
| 5 | 85.44 | 84.87 | |