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. 2021 Feb 3;11(11):6060–6098. doi: 10.1039/d0ra10657g

Anti-inflammatory activities of compounds (60–63) (reproduced with permission from O. I. Abd El-Salam, et al., Egypt. J. Chem., 2012, 55, 529–547, © 2012, Egyptian Chemical Society)90.

Compound no. Anti-inflammatory activity
Dose, mg kg−1 p.o. % inhibition of oedema % inhibition of PGE2
60 2.5 80.55 90.98
5 89.35 96.89
61 2.5 85.32 83.98
5 91.06 90.00
62 2.5 82.98 77.98
5 87.98 86.00
63 2.5 94.20 85.31
5 95.88 92.09
Diclofenac potassium 2.5 81.09 75.89
5 85.44 84.87