Table 2.
Characteristics and laboratory indices among patients with high and low nutritional risk.
| High-nutritional-risk group (mNUTRIC-Score ≥5, n = 46) |
Low-nutritional-risk group (mNUTRIC-Score <5, n = 52) |
p value | |
|---|---|---|---|
| Clinical characteristics | |||
| Female, n (%) | 19 (41.3%) | 12 (23.1%) | 0.053 |
| Male, n (%) | 27 (58.7%) | 40 (76.9%) | |
| Age, mean | 61.91 ± 12.39 | 53.07 ± 13.49 | ≤0.001 |
| Comorbidities | 2 (0–7) | 1 (0–5) | ≤0.001 |
| Charlson comorbidity index | 4 (2–9) | 2 (0–5) | ≤0.001 |
| Biochemicals | |||
| Glucose (mg/dL) | 175 (88–452) | 162 (77–533) | 0.105 |
| Creatinine (mg/dL) | 2.04 (0.64–20.23) | 0.96 (0.39–2.34) | ≤0.001 |
| BUN (mg/dL) | 47.40 (13–137) | 27.50 (9–55) | ≤0.001 |
| Albumin (g/dL) | 2.47 ± 0.49 | 2.63 ± 0.46 | 0.115 |
| C-reactive protein (mg/dL) | 230.28 ± 150.89 | 171.77 ± 116.6 | 0.033 |
| Arterial blood gas | |||
| pH | 7.29 ± 0.14 | 7.34 ± 0.14 | 0.114 |
| PaCO2 (mmHg) | 38 (13–115) | 44 (14–163) | 0.378 |
| Bicarbonate (mmol/L) | 21.09 ± 7.06 | 24.19 ± 4.93 | 0.013 |
| Lactate (mmol/L) | 2.10 (0.70–7) | 2 (0.60–4.9) | 0.889 |
| PaO2/FiO2 (mmHg) | 69 (33–366) | 84 (31–360) | 0.020 |
| Outcomes | |||
| Mechanical ventilation (days) | 10 (3–33) | 10 (3–40) | 0.162 |
| Total mNUTRIC-Score, median (IQR), points | 6 (5–8) | 2 (0–4) | ≤0.001 |
| Hospital length of stay (days) | 10.5 (2–34) | 15 (2–96) | 0.004 |
| Death at 28th day, n (%) | 42 (91.3%) | 29 (55.8%) | ≤0.001 |
| Initial nutrition therapy (hours) | 48 (12–168) | 76 (12–240) | 0.208 |
| Initial time of nutrition support | |||
| ≤48 h, n (%) | 18 (39.1%) | 17 (32.7%) | 0.193 |
| >48 h, n (%) | 15 (32.6%) | 26 (50%) | |
| Complications, n (%) | |||
| Acute kidney injury, n (%) | 34 (73.9%) | 28 (53.8%) | 0.004 |
| Upper gastrointestinal bleeding, n (%) | 2 (4.3%) | 4 (7.7%) | 0.491 |
| Vasopressors, n (%) | 27 (58.7%) | 23 (44.2%) | 0.153 |
Abbreviations: BUN, blood urea nitrogen; mNUTRIC-Score, modified Nutrition Risk in the Critically Ill-Score; IQR, interquartile range; PaCO2, arterial partial carbon dioxide pressure; PaO2/FiO2 ratio, partial pressure of arterial oxygen to fraction of inspired oxygen.