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. 2021 Dec 15;2021:2510195. doi: 10.1155/2021/2510195

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Copyright © 2021 Junjie Li et al.

This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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Different patterns of p53 expression in GI-NENs. (a) Pattern A showed completely absent p53 expression of tumor cell nucleus. Note that scattered stromal cells were weakly positive for p53 (40x). (b) Pattern B showed p53 expression in 1%-20% of tumor cell nuclei with weak intensity (40x). (c) Pattern C1 showed a variable staining intensity with focal tumor cell nests demonstrating strong positivity (40x). (d) Pattern C2 was accompanied by diffuse (61%-100%) and strong nuclear staining (40x).