TABLE 1.

PCV isolates used in this study as well as those reported previously

Type	Isolate no.	Geographic location	IHC		ISHa of PCV	Clinical sign(s)b	Histopathological lesionsc	Reference or source
			PRRSV	PCV
PCV-2	26606d	Utah	+	NDe	+	Resp	Pneumonia, lymphoid depletion, enteritis	This study
	26607d	Utah	+	ND	+	Resp, diarrhea	Pneumonia, enteritis, hepatitis, nephritis	This study
	40856d	Missouri	+	+	ND	Resp, wasting	Pneumonia, lymphoid depletion, hepatitis, nephritis	This study
	40895d	Iowa	−	+	ND	Resp, wasting	Pneumonia, lymphoid depletion	This study
	34464d	Canada	+	+	ND	Resp	Pneumonia	This study
	10489d	Illinois	−	+	ND	Resp, wasting	Pneumonia, lymphoid depletion	This study
	38835	Iowa	+	+	ND	Resp	Pneumonia, lymphoid depletion	This study
	36688	Iowa	+	+	ND	Resp, wasting, dermatitis	Pneumonia, lymphoid depletion, nephritis, dermatitis	This study
	40860	Iowa	+	+	ND	Resp	Pneumonia	This study
	40887	Iowa	+	+	ND	Resp	Pneumonia	This study
	AF055391	California						37
	AF027217	California						19
	AF109397	Francef						29, GenBank
	AJ223185	Iowa						39
	AF055394	France						37
	AF085695	Canada						GenBank
	AF086836	Canada						GenBank
	AF086835	Canada						GenBank
	AF086834	Canada						GenBank
	AF112862	Canada						GenBank
	AF166528	Taiwan						GenBank
	AF109399	Canada						GenBank
	AF109398	Canada						GenBank
	AF117753	Canada						GenBank
	AF055393	France						37
	AF055392	Canada						37
PCV-1	AF071879	PK15 cell						42
	Y09921	Germany						31
	U49186	Ireland						36
	AF012107	France						31

^aISH, in situ hybridization. 

^bClinical signs: Resp, respiratory disease; wasting, anorexia and weight loss. 

^cHistopathological lesions: pneumonia, interstitial pneumonia. 

^dPCV-2 isolates sequenced in this study. 

^eND, not determined. 

^fBovine isolate.