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. 2021 Dec 23;185(4):603–613.e15. doi: 10.1016/j.cell.2021.12.026

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Figure S4 — Peptide stimulation of Jurkat cell lines expressing the predicted S_167–180 specific TCRs, related to Figure 2

(A and B) NFAT-GFP reporter expression.

(C and D) CD69 surface expression. Incubation without peptide (unstimulated) and with irrelevant SARS-CoV-2 derived DPB1^∗04-restricted peptide (RSFIEDLLFNKVTLA described in Dykema et al. 2021 and Loyal et al. 2021) as well as stimulation of line expressing irrelevant TCR (specific to NQKLIANQF epitope from the spike protein of SARS-CoV-2, described in (Minervina et al., 2021b) with CTFEYVSQPFLMDLE peptide were used as negative controls.