表 2.
主要研究终点和次要研究终点
Primary and secondary outcomes
| Variables | Before matching | After matching | ||||||
| GA group(n=166) | EGA group(n =98) | P | GA group(n =87) | EGA group(n =87) | HR, OR or difference (95%CI) | P | ||
| GA, general anesthesia; EGA, combined epidural-general anesthesia; CI, confidence interval; HR, hazard ratio; OR, odds ratio; LOS=length of in-hospital stay; IQR, interquartile range. | ||||||||
| Primary outcome | ||||||||
| Overall survival, death, n (%) | 28 (16.9) | 9 (9.2) | 0.091 | 14 (16.1) | 5 (5.7) | HR=0.34 (0.12, 0.96) | 0.041 | |
| Secondary outcome, n (%) | ||||||||
| Total incidence of complications | 32 (19.3) | 10 (10.2) | 0.052 | 16 (18.4) | 7 (8.0) | OR=0.39 (0.15, 1.00) | 0.044 | |
| Individualized complications | ||||||||
| Ischemic cardiac events | 2 (1.2) | 0 (0) | 0.531 | 1 (1.1) | 0 (0) | OR=0.99 (0.97, 1.01) | 1.000 | |
| Hypertension | 24 (14.5) | 5 (5.1) | 0.019 | 12 (13.8) | 4 (4.6) | OR=0.30 (0.09, 0.97) | 0.036 | |
| Heart failure | 3 (1.8) | 0 (0) | 0.297 | 2 (2.3) | 0 (0) | OR=0.98 (0.95, 1.10) | 0.497 | |
| Arrythmia | 4 (2.4) | 3 (3.1) | 0.713 | 0 (0) | 1 (1.1) | OR=1.01 (0.99, 1.04) | 1.000 | |
| Atelectasis | 1 (0.6) | 0 (0) | 1.000 | 1 (1.1) | 0 (0) | OR=0.99 (0.97, 1.01) | 1.000 | |
| Pneumonia | 2 (1.2) | 1 (1.0) | 1.000 | 1 (1.1) | 1 (1.1) | OR=1.00 (0.06, 16.25) | 0.751 | |
| Hydrothorax | 5 (3.0) | 0 (0) | 0.161 | 3 (3.4) | 0 (0) | OR=0.97 (0.93, 1.01) | 0.246 | |
| Deep venous thrombi | 0 (0) | 2 (2.0) | 0.137 | 0 (0) | 2 (2.3) | OR=1.02 (0.99, 1.06) | 0.497 | |
| Postoperative LOS/day, median (IQR) | 11 (9, 14) | 11 (9, 14) | 0.810 | 11 (9, 13) | 11 (9, 14) | Difference=0 (-1.0, 1.0) | 0.783 | |