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. 2021 Feb 25;11(15):8741–8750. doi: 10.1039/d0ra09934a

ANOVA data of regression parameters of the central composition design experimenta.

Y 1 Y 2
Sum of squares F-Value p-Value probability Sum of squares F-Value p-Value probability
Model 113.66 15.54 <0.0001* 39.5 16.9 < 0.0001*
X 1 68.85 84.73 <0.0001* 22.48 86.54 < 0.0001*
X 2 0.6154 0.7573 0.4046 0.1747 0.6726 0.4313
X 3 8.64 10.63 0.0086* 3.64 14.01 0.0038*
X 1 X 2 0.3805 0.4682 0.5094 0.1572 0.6051 0.4547
X 1 X 3 4.96 6.11 0.033* 2.34 8.99 0.0134*
X 2 X 3 2.15 2.64 0.1349 0.9275 3.57 0.0881
X 1 2 1.45 1.78 0.2116 0.6556 2.52 0.1432
X 2 2 24.33 29.95 0.0003* 8.3 31.94 0.0002*
X 3 2 1.54 1.9 0.1983 0.5048 1.94 0.1935
Residual 8.13 2.6
Lack of fit 1.58 0.2418 0.9273** 0.5997 0.3002 0.8937**
Pure error 6.54 2
Cor total 121.79 42.1
Std. dev. 0.9014 0.5097
Mean 14.78 8.61
C.V. (%) 6.1 5.92
PRESS 22.37 7.96
R-Squared 0.9333 0.9383
Adjusted R-squared 0.8732 0.8828
Predicted R-squared 0.8163 0.8109
a

* Indicate the significance at p-value <0.05. ** Indicate the insignificance at p-value <0.05.