In vivo biochemical evaluation of fasting blood glucose (FBG), insulin (INS), homeostasis model assessment of insulin resistance (HOMA-IR) and glucose transporter 4 (Glut 4) among the different groups.
Groups | FBG (mmol L−1) | INS (μIU mL−1) | HOMA-IR | GLUT 4 (ng mL−1) |
---|---|---|---|---|
Normal control | 4.79 ± 0.12a | 11.23 ± 0.58a | 2.45 ± 0.14a | 11.66 ± 0.12a |
Diabetic rats | 21.41 ± 0.45b | 43.13 ± 4.67b | 41.38 ± 3.67b | 8.61 ± 0.44b |
Plain extract treated group | 12.10 ± 1.25a,b | 35.03 ± 4.48b | 20.38 ± 3.78a,b | 8.42 ± 0.38b |
Standard drug treated group | 11.86 ± 0.92a,b | 26.30 ± 4.05a | 13.10 ± 2.07a | 9.17 ± 0.66b |
Nano-extract treated group | 7.88 ± 0.44a | 13.50 ± 2.14a | 4.82 ± 0.96a | 11.27 ± 0.42a |
P < 0.05 versus diabetic rats.
P < 0.05 versus normal control.