表 1.
倾向评分匹配法匹配前及匹配后患者临床病理信息
Clinicopathological characteristics between two period before and after propensity-score matching
| Variables | Before propensity-score matching | After propensity-score matching | |||||
| Early phase (n=660) |
Late phase (n=2, 221) |
P | Early phase (n=634) |
Late phase (n=634) |
P | ||
| Values are mean±SD or median (IQR) or n (%) unless otherwise noted. ASA: American Society of Anesthesiologists; BMI: body mass index; CCI: charlson comorbidity index; DLCO: diffusing capacity of the lungs for carbon monoxide; FEV1: forced expiratory volume in one second; IQR: interquartile range; SD: standard deviation. | |||||||
| Gender | |||||||
| Male | 346 (52.4) | 1, 124 (50.6) | 0.412 | 327 (51.6) | 348 (54.9) | 0.237 | |
| Famale | 314 (47.6) | 1, 097 (49.4) | 307 (48.4) | 286 (45.1) | |||
| Age (yr) | 62.3±10.6 | 60.6±9.9 | < 0.001 | 62.0±10.6 | 60.8±10.3 | 0.043 | |
| Smoking history | |||||||
| None | 400 (60.6) | 1, 435 (64.6) | 0.060 | 394 (62.1) | 362 (57.1) | 0.067 | |
| Yet | 260 (39.4) | 786 (35.4) | 240 (37.9) | 272 (42.9) | |||
| BMI (kg/m2) | 24.0±3.2 | 24.5±12.8 | 0.292 | 24.0±3.2 | 24.0±3.3 | 0.976 | |
| CCI | |||||||
| 0 | 497 (75.3) | 1, 718 (77.4) | 0.237 | 478 (75.4) | 507 (80.0) | 0.281 | |
| 1 | 121 (18.3) | 366 (16.5) | 116 (18.3) | 97 (15.3) | |||
| 2 | 29 (4.4) | 114 (5.1) | 28 (4.4) | 22 (3.5) | |||
| 3 | 11 (1.7) | 20 (0.9) | 10 (1.6) | 8 (1.3) | |||
| 4 | 1 (0.2) | 2 (0.1) | 1 (0.2) | 0 (0.0) | |||
| ≥5 | 0 (0.0) | 1 (0.0) | 1 (0.2) | 0 (0.0) | |||
| Diameter of main lesion (cm) | 2.6±1.4 | 2.4±1.5 | 0.016 | 2.6±1.4 | 2.5±1.6 | 0.441 | |
| FEV1 (L) | 2.6±4.1 | 2.6±2.6 | 0.833 | 2.5±0.7 | 2.5±0.6 | 0.026 | |
| FEV1% | 94.0±17.4 | 96.5±17.2 | 0.002 | 94.5±16.8 | 95.0±17.5 | 0.603 | |
| ASA | |||||||
| Ⅰ | 101 (15.3) | 348 (15.7) | 0.760 | 100 (15.8) | 122 (19.2) | 0.242 | |
| Ⅱ | 523 (79.2) | 1, 766 (79.5) | 499 (78.7) | 485 (76.5) | |||
| Ⅲ | 35 (5.3) | 106 (4.8) | 34 (5.4) | 27 (4.3) | |||
| Ⅳ | 1 (0.2) | 1 (0.0) | 1 (0.2) | 0 (0.0) | |||
| Operation time (min) | 189±55 | 160±49 | < 0.001 | 186±53 | 185±55 | 0.86 | |
| Tumor location | |||||||
| Right upper lobe | 239 (36.2) | 762 (34.3) | 0.634 | 229 (36.1) | 222 (35.0) | 0.724 | |
| Right lower lobe | 124 (18.8) | 447 (20.1) | 60 (9.5) | 55 (8.7) | |||
| Right middle lobe | 61 (9.2) | 210 (9.5) | 119 (18.8) | 112 (17.7) | |||
| Left upper lobe | 144 (21.8) | 453 (20.4) | 139 (21.9) | 141 (22.2) | |||
| Left lower lobe | 92 (13.9) | 349 (15.7) | 87 (13.7) | 104 (16.4) | |||
| Procedure | |||||||
| Lobectomy | 635 (96.2) | 2, 126 (95.7) | 0.198 | 611 (96.4) | 603 (95.1) | 0.19 | |
| Bilobectomy | 18 (2.7) | 46 (2.1) | 16 (2.5) | 15 (2.4) | |||
| Pneumonectomy | 4 (0.6) | 22 (1.0) | 4 (0.6) | 5 (0.8) | |||
| Sleeve lobectomy | 3 (0.5) | 27 (1.2) | 3 (0.5) | 11 (1.7) | |||
| Blood loss (mL) | 100 (50-200) | 30 (50-100) | < 0.001 | 100 (50-200) | 50 (30-100) | < 0.001 | |
| Dissected nodal stations | 6±2 | 6±1 | 0.016 | 6±2 | 7±2 | < 0.001 | |
| Dissected lymph nodes | 18±8 | 15±7 | < 0.001 | 18±8 | 18±8 | 0.894 | |
| Histologic subtype | |||||||
| Squamous cell | 95 (14.4) | 291 (13.1) | 0.094 | 88 (13.9) | 93 (14.7) | 0.586 | |
| Adenocarcinoma | 511 (77.4) | 1, 800 (81.0) | 496 (78.2) | 479 (75.6) | |||
| Small cell | 11 (1.7) | 33 (1.5) | 11 (1.7) | 16 (2.5) | |||
| Others | 43 (6.5) | 97 (4.4) | 39 (6.2) | 46 (7.3) | |||
| Pathological stage | |||||||
| Ⅰ | 445 (67.4) | 1, 600 (72.0) | 0.072 | 427 (67.4) | 416 (65.6) | 0.689 | |
| Ⅱ | 100 (15.2) | 291 (13.1) | 95 (15.0) | 106 (16.7) | |||
| Ⅲ | 115 (17.4) | 330 (14.9) | 112 (17.7) | 112 (17.7) | |||