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. 2021 Dec 23;5:26. doi: 10.1186/s41824-021-00121-2

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© The Author(s) 2021

Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.

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Fig. 2 — ¹⁸F-THK5351 PET images 46 days (A) and 271 days (B) after the injury. The rainbow color bar represents the normalized uptake of ¹⁸F-THK5351, with cerebellar uptake set as one. A PET images showed increased uptake of ¹⁸F-THK5351 in the right frontal and temporal lobes and in the left frontal lobe and increased ¹⁸F-THK5351 uptake with a ring-like pattern around the brain contusion in the right frontal lobe (black arrow heads). B PET images showed reduced uptake of ¹⁸F-THK5351 in the original sites of brain contusions in the right frontal and temporal lobes and in the left frontal lobe. Increased ¹⁸F-THK5351 uptakes were observed in the white matter surrounding the brain contusions (red arrows) and the corpus callosum (white arrows)