I2-mediated sulfenylation and sulfonylation of 2-naphthols with sodium sulfinates.
Thioethers | Method-A | Sulfones | Method-B |
---|---|---|---|
R = H: 80% | R = H: 82% | ||
R = F: 70% | R = F: 73% | ||
R = Br: 75% | R = Br: 77% | ||
R = Cl: 75% | R = Cl: 75% | ||
R = Me: 89% | R = Me: 84% | ||
R = CF3: 71% | R = CF3: 67% | ||
R = OMe: 85% | R = OMe: 72% | ||
R = OCF3: 66% | R = OCF3: 70% | ||
R = Me: 60% | R = Me: 68% | ||
R = n-Pr: 80% | R = n-Pr: 45% |