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. 2021 Dec 22;11:24392. doi: 10.1038/s41598-021-03461-y

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© The Author(s) 2021

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.

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Salivary viral loads for all five treatment groups through time. Box plots show viral load levels, as measured by qPCR, for each of the patients in the group A—PVP-I (povidone-iodine), B—Hydrogen peroxide (H₂O₂), C—CPC (cetylpyridinium chloride), D—CHX (chlorhexidine) and E—Distilled water (placebo group) at the four different timepoints (1 for basal and 2, 3 and 4 for the three times after the mouthwash, corresponding to 30, 60 and 120 min after the mouthwash, respectively). Lines joining the samples from the same patient are also shown.