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. 2021 Dec 22;11:24392. doi: 10.1038/s41598-021-03461-y

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© The Author(s) 2021

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.

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Relative changes in salivary viral load for all five treatment groups after the mouthwash. Box plots show changes of viral load (%) for each of the patients in the group A—PVP-I (povidone-iodine), B—H₂O₂, C—CPC (cetylpyridinium chloride), D—CHX (chlorhexidine) and E (placebo group) at the three different times after the oral rinse treatment, relative to the baseline viral load prior to the mouthwash (changes at 30 min: t2–t1; changes at 60 min: t3–t1; changes at 120 min: t4–t1). Lines joining the points from the same patient through time are also shown.