Table 2.
Antipsychotic Use and Dose by Medication Type (N = 283 Residents, 325 Medications).
| Medication type and names | N (%) of residents taking the drug | Daily dose | Daily dose equivalence a | |
|---|---|---|---|---|
| Median (IQR) | Range | Median (IQR) | ||
| First generation/typical | ||||
| Haloperidol (Haldol) | 11 (3.9) | 1.3 (1.0–2.0) | 0.25–8.0 | 65.0 (50.0–100.0) |
| Perphenazine (Trilafon) | 1 (0.4) | 4.0 | 4.0 | 50.0 |
| Second generation/atypical | ||||
| Aripiprazole (Abilify) | 8 (2.8) | 5.0 (2.0–5.0) | 2.0–5.0 | 66.7 (26.7–66.7) |
| Olanzapine (Zyprexa) | 35 (12.4) | 5.0 (2.5–10.0) | 1.25–25.0 | 100.0 (50.0–200.0) |
| Quetiapine (Seroquel) | 165 (58.3) | 50.0 (25.0–100.0) | 0.5–600.0 | 66.7 (33.3–133.3) |
| Risperidone (Risperdal) | 74 (26.1) | 0.5 (0.5–1.0) | 0.125–6.0 | 50.0 (50.0–100.0) |
| Ziprasidone (Geodon) | 4 (1.4) | 70.0 (50.0–80.0) | 40.0–80.0 | 116.7 (83.3–133.3) |
Note. Source = resident charts. IQR = interquartile range; daily dose = strength in milligrams × daily frequency.
a
Based on 100 mg of chloropromazine: haloperidol dose × 50.0 mg, perphenazine dose × 12.5 mg, aripiprazole dose × 13.3 mg; olanzapine dose × 20.0 mg, quetiapine dose ×1.3 mg, risperidone dose × 100.0 mg, ziprasidone dose × 1.6 mg (College of Psychiatric & Neurologic Pharmacists, 2019; Leucht et al., 2014, 2016).