Skip to main content
. 2021 Mar 17;11(19):11062–11082. doi: 10.1039/d0ra10932k

Target genes in 13 signaling pathways enrichment related to obesity.

KEGG ID & description Target genes False discovery rate
has03320: PPAR signaling pathway NR1H3, PPARA, FABP3, FABP4, PPARG, PPARD 0.0000333
hsa04919: thyroid hormone signaling pathway PRKCA, AKT1, ESR1, THRA, THRB 0.0012
hsa04917: prolactin signaling pathway AKT1, ESR1, ESR2, CYP17A1 0.0019
hsa04370: VEGF signaling pathway AKT1, PRKCA, PLA2G4A 0.012
hsa04072: phospholipase D signaling pathway AKT1, PRKCA, PLA2G4A, LPAR5 0.0138
hsa04723: retrograde endocannabinoid signaling PRKCA, CNR1, MGLL, FAAH 0.014
hsa04664: Fc epsilon RI signaling pathway AKT1, PRKCA, PLA2G4A 0.014
hsa04662: B cell receptor signaling pathway AKT1, PTPN6, CD81 0.0143
hsa04660: T cell receptor signaling pathway AKT1, PTPRC, PTPN6 0.0259
hsa04015: Rap1 signaling pathway AKT1, PRKCA, CNR1, LPAR5 0.0259
hsa04014: ras signaling pathway AKT1, PRKCA, PLA2G4A, PLA2G2A 0.0347
hsa04915: estrogen signaling pathway AKT1, ESR1, ESR2 0.0433
hsa04910: insulin signaling pathway AKT1, PTPN1, PTPRF 0.0433