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. 2021 Dec 9;12:798859. doi: 10.3389/fimmu.2021.798859

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Copyright © 2021 Pinilla, Heinzel, Caminada, Consolaro, Esen, Kremsner, Held, Kreidenweiss and Fendel

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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SARS-CoV-2 RBD reactive IgG over a 15-month follow-up period. Samples were collected 5 times, bimonthly from 72 convalesced volunteers who had mild COVID-19. IgG kinetics are shown per individual (black line). Sampling time points (black dots) are given as days post symptom onset (PSO). Blue line: regression line. Red dotted line: Cut-off for positivity. (A) IgG (µg/ml) kinetics in plasma after COVID-19 convalescence. Slope of linear regression = -0.02, p = 0.2. (B) IgG (ng/ml) kinetics in saliva after COVID-19 convalescence. Slope of linear regression = 0.009, p = 0.7.