Table 3.
Clinical performance characteristics of double lectins for the CRC matrix with the best combinations showed in red.
| Lectins | AUC | AUC left | AUC right | Spec | Sens | Acc | AUCage/AUCCRC |
|---|---|---|---|---|---|---|---|
| PHAE + AAL | 0.972 | 0.9 | 1 | 0.944 | 0.9 | 0.929 | 0.772 |
| PHAE + HPyL | 0.961 | 0.883 | 1 | 0.833 | 1 | 0.893 | 0.798 |
| PHAE + PHAL | 0.944 | 0.844 | 1 | 0.778 | 1 | 0.857 | 0.707 |
| PHAE + RCA I | 0.95 | 0.856 | 1 | 0.944 | 0.9 | 0.929 | 0.719 |
| PHAE + RPL-Sia2 | 0.939 | 0.828 | 1 | 0.833 | 1 | 0.893 | 0.674 |
| PHAE + P sel | 0.956 | 0.861 | 1 | 0.944 | 0.9 | 0.929 | 0.698 |
| PHAE + HL sel | 0.989 | 0.95 | 1 | 1 | 0.9 | 0.964 | 0.741 |
| RCA I + PHAE | 0.95 | 0.856 | 1 | 0.944 | 0.9 | 0.929 | 0.719 |
| RCA I + HL sel | 0.961 | 0.883 | 1 | 1 | 0.8 | 0.929 | 0.746 |
| RCA I + HE sel | 0.9 | 0.75 | 1 | 0.944 | 0.8 | 0.893 | 0.703 |
| HL sel + AAL | 0.911 | 0.778 | 1 | 0.833 | 0.9 | 0.857 | 0.659 |
| HL sel + HPyL | 0.911 | 0.778 | 1 | 1 | 0.7 | 0.893 | 0.64 |
| HL sel + PHAE | 0.989 | 0.95 | 1 | 1 | 0.9 | 0.964 | 0.741 |
| HL sel + PHAL | 0.894 | 0.761 | 0.994 | 0.944 | 0.7 | 0.857 | 0.671 |
| HL sel + RCA I | 0.961 | 0.883 | 1 | 1 | 0.8 | 0.929 | 0.746 |
| HL sel + RPL-Fuc1 | 0.917 | 0.789 | 1 | 1 | 0.7 | 0.893 | 0.69 |
| HL sel + RPL-Sia2 | 0.906 | 0.761 | 0.994 | 0.944 | 0.7 | 0.857 | 0.681 |
| HL sel + P sel | 0.889 | 0.728 | 1 | 1 | 0.7 | 0.893 | 0.75 |
| HL sel + HE sel | 0.922 | 0.8 | 0.994 | 0.833 | 0.9 | 0.857 | 0.651 |
see Table 2 . Only lectin combinations with the ratio of AUCage/AUCCRC below 0.8 are shown.