Intramolecular Tishchenko reaction of aromatic dialdehydesa.
| |||||
|---|---|---|---|---|---|
| Entry | Aldehyde | Ir (5a) | i PrOH | K2CO3 (x mol%) | Yield (%) |
| 1 | 6a | + | + | 20 | 97 |
| 2 | 6a | — | + | 20 | 0 |
| 3 | 6a | + | — | 20 | 24 |
| 4 | 6a | + | + | — | 6 |
| 5 | 6a | + | + | 10 | 28 |
| 6 | 6b | + | + | 20 | 97 |
All the reactions were carried out on a 0.15 mmol scale of 6.