TABLE 3.
Diagnostic efficacy of bilateral differential topographic characteristics.
| Parameters | AUROC | Sig. | 95% CI | Cut-off | Sensitivity (%) | Specificity (%) |
|---|---|---|---|---|---|---|
| ΔFKmax (D) | 0.982 | <0.001 | 0.970∼0.995 | 2.56 | 95.7 | 95.4 |
| ΔFKmean (D) | 0.985 | <0.001 | 0.973∼0.997 | 0.75 | 95.7 | 96.0 |
| ΔFKsd (D) | 0.985 | <0.001 | 0.974∼0.996 | 0.67 | 95.0 | 97.7 |
| ΔFEmax (μm) | 0.983 | <0.001 | 0.972∼0.995 | 14.6 | 95.0 | 95.4 |
| ΔFEmean (μm) | 0.982 | <0.001 | 0.968∼0.997 | 4.3 | 95.7 | 96.0 |
| ΔFEsd (μm) | 0.984 | <0.001 | 0.972∼0.996 | 2.9 | 96.9 | 94.8 |
| ΔBEmax (μm) | 0.918 | <0.001 | 0.887∼0.949 | 36.3 | 85.7 | 85.6 |
| ΔBEmean (μm) | 0.963 | <0.001 | 0.941∼0.985 | 9.9 | 93.2 | 92.5 |
| ΔBEsd (μm) | 0.952 | <0.001 | 0.929∼0.974 | 7.6 | 88.8 | 89.1 |
| ΔCPmax (μm) | 0.698 | <0.001 | 0.639∼0.757 | 38.4 | 65.2 | 65.5 |
| ΔCPmean (μm) | 0.759 | <0.001 | 0.705∼0.814 | 13.2 | 69.6 | 70.7 |
| ΔCPsd (μm) | 0.761 | <0.001 | 0.706∼0.815 | 8.5 | 70.8 | 70.7 |
ΔFKmax = the maximal front keratometry value within 1.5 mm radius of the bilateral differential topography; ΔFKmean = the mean front keratometry value within 1.5 mm radius of the bilateral differential topography; ΔFKsd = the standard deviation of the front keratometry values within 1.5 mm radius of the bilateral differential topography; ΔFEmax = the maximal front elevation value within 1.5 mm radius of the bilateral differential topography; ΔFEmean = the mean front elevation value within 1.5 mm radius of the bilateral differential topography; ΔFEsd = the standard deviation of the front elevation values within 1.5 mm radius of the bilateral differential topography; ΔBEmax = the maximal back elevation value within 1.5 mm radius of the bilateral differential topography; ΔBEmean = the mean back elevation value within 1.5 mm radius of the bilateral differential topography; ΔBEsd = the standard deviation of the back elevation values within 1.5 mm radius of the bilateral differential topography; ΔCPmax = the maximal corneal pachymetry value within 1.5 mm radius of the bilateral differential topography; ΔCPmean = the mean corneal pachymetry value within 1.5 mm radius of the bilateral differential topography; ΔCPsd = the the standard deviation of the corneal pachymetry values within 1.5 mm radius of the bilateral differential topography; AUROC = area under the receiver operating characteristic curve; Sig = significance; CI = confidence interval; D = dioptor; μm = micron.